\u3068\u3044\u3046\u540d\u524d\u306e\u7814\u7a76\u96c6\u4f1a\u3067\u3057\u3083\u3079\u3063\u3066\u304d\u305f\u3002\u767a\u8868\u306f\u304b\u306a\u308a\u624b\u5fdc\u3048\u304c\u3042\u308a\u3001\u3044\u308d\u3044\u308d\u306a\u65b9\u304b\u3089\u8cea\u554f\u3084\u3001\u4f7f\u3063\u3066\u307f\u305f\u3044\u3001\u3068\u3044\u3046\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u3044\u305f\u3002
\n\u50d5\u4ee5\u5916\u306e2\u4ef6\u306f\u75c5\u6c17\u95a2\u4fc2\u306e\u8a71\u3002\u75c5\u539f\u6027\u306e\u3042\u308b\u751f\u7269\u306e\u30b2\u30ce\u30e0\u306f\u3001\u3082\u306e\u3059\u3054\u3044\u52e2\u3044\u3067\u89e3\u8aad\u304c\u9032\u3093\u3067\u3044\u308b\u3053\u3068\u3092\u5b9f\u611f\u3057\u305f\u3002
\n\u4ee5\u4e0b\u30e1\u30e2\u3002
\n[\u539f\u866b\u306b\u304a\u3051\u308b\u819c\u8f38\u9001\u306e\u7279\u6b8a\u6027\u3068\u591a\u69d8\u6027: \u8d64\u75e2\u30a2\u30e1\u30fc\u30d0\u304b\u3089\u306e\u60c5\u5831\u767a\u4fe1]
\n\u611f\u67d3\u7814\u306e\u4e2d\u91ce\u5148\u751f\u3002
\n\u30a2\u30e1\u30fc\u30d0\u8d64\u75e2\u306e\u611f\u67d3\u80055000\u4e07\u4eba\u3001\u6b7b\u4ea14\u301c10\u4e07\u3002
\n\u56fd\u5185\u3067\u3082700\u4eba\u3002
\n\u63a5\u7740\u3001\u30d7\u30ed\u30c6\u30a2\u30fc\u30bc\u306e\u5206\u6ccc\u3068\u5bbf\u4e3b\u306e\u8a8d\u8b58\u3001\u30d5\u30a1\u30b4\u30bd\u30fc\u30e0\u3067\u306e\u5206\u89e3\u3001\u8caa\u98df\u306a\u3069\u3001\u3059\u3079\u3066\u819c\u8f38\u9001\u3068\u3057\u3066\u307f\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002
\n\u30b2\u30ce\u30e0\u306f\u89e3\u8aad\u3055\u308c\u3066\u304a\u308a\u300120Mbp \u304f\u3089\u3044\u30029800\u907a\u4f1d\u5b50\u3002
\nGTPase \u304c\u5c0f\u80de\u306e\u5f62\u6210\u3084\u5206\u89e3\u306b\u95a2\u4e0e\u3002
\nRab\u30bf\u30f3\u30d1\u30af\u8cea (Ras superfamily \u306b\u5165\u308b\u3001\u819c\u878d\u5408\u30bf\u30f3\u30d1\u30af\u8cea) \u306e\u591a\u69d8\u5316:
\n\u591a\u7d30\u80de\u5316\u3067\u7d44\u7e54\u7279\u7570\u7684\u306a\u8f38\u9001\u7cfb\u304c\u5fc5\u8981\u306b\u306a\u308b\u306e\u3067\u3001\u7a2e\u985e\u304c\u5897\u3048\u308b (\u30b2\u30ce\u30e0\u306b\u306f\u305f\u304f\u3055\u3093\u30b3\u30fc\u30c9\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u3072\u3068\u3064\u306e\u7d30\u80de\u3067\u52d5\u3044\u3066\u3044\u308b\u3084\u3064\u306f\u5c11\u306a\u3044) \u304c\u3001
\n\u8d64\u75e2\u30a2\u30e1\u30fc\u30d0\u3001\u30c6\u30c8\u30e9\u30d2\u30e1\u30ca\u3001\u30be\u30a6\u30ea\u30e0\u30b7\u3001\u30c8\u30ea\u30b3\u30e2\u30ca\u30b9\u3067\u306f\u30d2\u30c8\u3088\u308a\u591a\u304f\u3001\u7a2e\u7279\u7570\u7684\u306a\u3082\u306e\u304c\u591a\u3044\u3002\u3053\u3061\u3089\u306f\u3001\u30b2\u30ce\u30e0\u306b\u3082\u305f\u304f\u3055\u3093\u30b3\u30fc\u30c9\u3055\u308c\u3066\u304a\u308a\u3001\u767a\u73fe\u3057\u3066\u3044\u308b\u7a2e\u985e\u3082\u591a\u3044\u3002
\n\u30b2\u30ce\u30e0\u30b5\u30a4\u30ba\u306f\u7d30\u80de\u6027\u7c98\u83cc\u306a\u3093\u304b\u3068\u540c\u3058\u304f\u3089\u3044\u306a\u306e\u306b\u306d\u3002
\nRas \u30d5\u30a1\u30df\u30ea\u7684\u306b\u306f\u30a2\u30e1\u30fc\u30d0\u904b\u52d5\u3059\u308b\u3084\u3064\u3089\u304c Rho (\u30a2\u30af\u30c1\u30f3\u7d30\u80de\u9aa8\u683c) \u907a\u4f1d\u5b50\u3092\u3044\u3063\u3071\u3044\u3082\u3063\u3066\u3044\u308b\u3002
\nRab \u304c\u591a\u69d8\u5316\u3057\u305f\u9023\u4e2d\u306f\u3001Ras super family \u5168\u4f53\u304c\u5897\u3048\u3066\u3044\u308b\u308f\u3051\u3067\u306f\u306a\u304f\u3001Rab \u30d5\u30a1\u30df\u30ea\u3060\u3051\u304c\u5897\u3048\u3066\u3044\u308b\u3002\u7279\u5fb4\u3068\u3057\u3066\u306f\u3001
\n– \u30aa\u30eb\u30ac\u30cd\u30e9\u304c\u5927\u304d\u304f\u3001\u4e38\u3044
\n– \u30d5\u30a1\u30b4\u30b5\u30a4\u30c8\u30fc\u30b7\u30b9\u304c\u6d3b\u767a\u3067\u3001\u53d6\u308a\u8fbc\u307f\u304c\u901f\u3044
\n\u3068\u3044\u3046\u3053\u3068\u304c\u3042\u308a\u3001\u3064\u307e\u308a\u819c\u8f38\u9001\u304c\u6d3b\u767a\u3002
\n[ \u30de\u30e9\u30ea\u30a2\u539f\u866b SERA \u907a\u4f1d\u5b50\u30d5\u30a1\u30df\u30ea\u30fc\u306e\u7cfb\u7d71\u9032\u5316 ]
\n\u962a\u5927\u306e\u6709\u672b\u5148\u751f\u3002
\n\u5e74\u9593\u306e\u611f\u67d3\u8005\u65702\u301c3\u5104\u3001\u6b7b\u4ea1\u8005\u6570100\u301c300\u4e07\u3002\u307b\u3068\u3093\u3069\u304c\u5b50\u4f9b\u3002
\n\u30de\u30e9\u30ea\u30a2\u539f\u866b: \u809d\u7d30\u80de\u3067\u5897\u6b96\u3057\u3066\u8d64\u8840\u7403\u306b\u5165\u308b\u3002\u8d64\u8840\u7403\u306e\u4e2d\u3067\u5897\u3048\u3066\u8d64\u8840\u7403\u3092\u3076\u3063\u58ca\u3059 (\u3053\u3053\u3067\u306f\u3058\u3081\u3066\u30d2\u30c8\u306e\u514d\u75ab\u30b7\u30b9\u30c6\u30e0\u306b\u3055\u3089\u3055\u308c\u308b)\u3002
\n\u809d\u7d30\u80de\u671f\u30ef\u30af\u30c1\u30f3\u3001\u8d64\u8840\u7403\u671f\u30ef\u30af\u30c1\u30f3\u3001\u4f1d\u642c\u963b\u6b62\u30ef\u30af\u30c1\u30f3\u3002
\nSERA \u30ef\u30af\u30c1\u30f3\u306f SERA \u30bf\u30f3\u30d1\u30af\u8cea\u306eSerine repeat \u306e\u3068\u3053\u308d\u306b\u304f\u3063\u3064\u304f\u3002
\nSERA \u30bf\u30f3\u30d1\u30af\u8cea\u306f\u907a\u4f1d\u5b50\u30d5\u30a1\u30df\u30ea\u3092\u5f62\u6210\u3057\u3066\u304a\u308a\u3001protease domain \u304c\u3042\u308b (\u57fa\u672c\u7684\u306b serine protease \u3060\u304c\u3001cysteine protease \u306a\u30b0\u30eb\u30fc\u30d7\u3082\u3042\u308b)\u3002
\n\u30b7\u30be\u30f3\u30c8\u304b\u3089\u30e1\u30ed\u30be\u30a4\u30c8\u304c\u308f\u3063\u3068\u51fa\u3066\u304f\u308b\u904e\u7a0b\u306b\u95a2\u4e0e\u3057\u3001\u30e1\u30ed\u30be\u30a4\u30c8\u304c\u51fa\u3066\u3053\u3089\u308c\u306a\u3044\u3088\u3046\u306b\u3059\u308b\u3053\u3068\u3067\u611f\u67d3\u3092\u6291\u3048\u308b\u3002\u305d\u3053\u306e\u6a5f\u69cb\u306f\u970a\u9577\u985e\u30de\u30e9\u30ea\u30a2\u3068\u9f67\u6b6f\u985e\u30de\u30e9\u30ea\u30a2\u3067\u7570\u306a\u308b\u3002
\n\u306a\u3093\u3069\u3082\u611f\u67d3\u3057\u3066\u3082 SERA \u306b\u5bfe\u3059\u308b\u6297\u4f53\u4fa1\u304c\u4e0a\u304c\u3089\u306a\u3044\u3072\u3068\u304c\u3044\u308b\u3002\u3067\u3082\u3001SERA5 recombinant \u3092\u6ce8\u5c04\u3067\u5165\u308c\u3061\u3083\u3048\u3070\u4e0a\u304c\u3063\u3066\u3001\u30ef\u30af\u30c1\u30f3\u3068\u3057\u3066\u4f7f\u3048\u308b\u3002\u81e8\u5e8a\u5b9f\u9a13\u4e2d\u3002
\nSERA\u9593\u3067\u306e recombination \u3068\u304b gene conversion \u3082\u8d77\u304d\u3066\u3044\u308b\u6a21\u69d8\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"
\u3068\u3044\u3046\u540d\u524d\u306e\u7814\u7a76\u96c6\u4f1a\u3067\u3057\u3083\u3079\u3063\u3066\u304d\u305f\u3002\u767a\u8868\u306f\u304b\u306a\u308a\u624b\u5fdc\u3048\u304c\u3042\u308a\u3001\u3044\u308d\u3044\u308d\u306a\u65b9\u304b\u3089\u8cea\u554f\u3084\u3001\u4f7f\u3063\u3066\u307f\u305f\u3044\u3001\u3068\u3044\u3046\u30b3\u30e1\u30f3\u30c8\u3092\u3044\u305f\u3060\u3044\u305f\u3002 \u50d5\u4ee5\u5916\u306e2\u4ef6\u306f\u75c5\u6c17\u95a2\u4fc2\u306e\u8a71\u3002\u75c5\u539f\u6027\u306e\u3042\u308b\u751f\u7269\u306e\u30b2\u30ce\u30e0\u306f\u3001\u3082\u306e\u3059\u3054\u3044\u52e2\u3044\u3067\u89e3\u8aad\u304c\u9032\u3093\u3067\u3044\u308b … “\u3064\u304f\u3070\u85fb\u985e\u30fb\u30d7\u30ed\u30c6\u30a3\u30b9\u30c8\u30d5\u30a9\u30fc\u30e9\u30e0” \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"activitypub_content_warning":"","activitypub_content_visibility":"","activitypub_max_image_attachments":4,"activitypub_interaction_policy_quote":"anyone","activitypub_status":"","footnotes":""},"categories":[10],"tags":[],"class_list":["post-2455","post","type-post","status-publish","format-standard","hentry","category-conference-logs"],"_links":{"self":[{"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/posts\/2455","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/comments?post=2455"}],"version-history":[{"count":0,"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/posts\/2455\/revisions"}],"wp:attachment":[{"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/media?parent=2455"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/categories?post=2455"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/yasu2.prosou.nu\/blog\/index.php\/wp-json\/wp\/v2\/tags?post=2455"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}